Different hemoglobin thresholds for transfusion in patients with severe sepsis and septic shock

نویسندگان

  • T Kamio
  • M Sanui
  • M Hayakawa
  • D Kudo
  • K Yamakawa
  • Y Iizuka
  • S Saito
  • K Takimoto
  • S Uchino
  • T Mayumi
  • Y Sasabuchi
چکیده

Introduction Hemoglobin (Hb) level transfusion thresholds in patients with sepsis who develop anemia have long been a matter of debate. In a randomized controlled trial comparing thresholds of Hb ≤ 7 g/dL vs. ≤ 9 g/dL in patients with severe sepsis and septic shock, comparable outcomes including mortality were obtained [1], while in an observational study of those patients, higher Hb levels were associated with lower mortality [2]. During the resuscitation phase of septic shock, a substantial number of clinicians may have used a higher threshold of hemoglobin at 10 g/dL, as recommended in the Surviving Sepsis Campaign Guideline 2008 [3].

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2015